Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661611 | 0.91 | GRM4 (0.38) | GRM4JAK2JAK1TYK2HTT | |
| SCHEMBL8662433 | 0.81 | DHODH (0.36) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL9136067 | 0.80 | NPC1 (0.36) | HTTALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL10793780 | 0.76 | SCN9A (0.41) | ALDH1A1MAPTKDM4ELMNANPSR1 | |
| SCHEMBL9134262 | 0.74 | ALDH1A1 (0.41) | HTTALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8658782 | 0.72 | MEN1 (0.41) | ALDH1A1MAPTKDM4EKMT2APOLB | |
| SCHEMBL8662542 | 0.71 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ASMN1; SMN2POLB | |
| SCHEMBL8659442 | 0.69 | ALDH1A1 (0.48) | ALDH1A1LMNASMN1; SMN2POLBMAPK1 | |
| SCHEMBL8660981 | 0.69 | KDM4E (0.44) | JAK2JAK1TYK2ALDH1A1MAPT | |
| SCHEMBL11097980 | 0.67 | MEN1 (0.43) | JAK2JAK1TYK2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |