Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 5/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | DUSP1 | P28562 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657630 | 0.92 | POLB (0.47) | ESRRASMOMEN1KMT2AMAPT | |
| SCHEMBL8658892 | 0.91 | ESRRA (0.46) | ESRRASMOKMT2AMAPTALDH1A1 | |
| SCHEMBL8659316 | 0.90 | ESRRA (0.50) | ESRRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9133955 | 0.89 | ESRRA (0.39) | ESRRASMOMEN1KMT2AMAPT | |
| SCHEMBL8656606 | 0.87 | MEN1 (0.43) | ESRRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8661001 | 0.86 | ESRRA (0.48) | ESRRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8656131 | 0.85 | ESRRA (0.51) | ESRRASMOMAPTALDH1A1LMNA | |
| SCHEMBL10774873 | 0.85 | DUSP1 (0.40) | SMOMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9137555 | 0.84 | ALDH1A1 (0.54) | ESRRAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL9135808 | 0.83 | ESRRA (0.48) | ESRRAMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124282-B1 | BICYCLOOXYARYL THIOUREAS AND PROCESS FOR PREPARATION | UNION CARBIDE CORPORATION (US) | 1987-09-30 | — | — | EP | claimed |
| US-4665097-A | Novel bicyclooxyaryl thioureas and process for preparation | UNION CARBIDE CORPORATION (US) | 1987-05-12 | — | — | US | claimed |
| EP-0124282-A1 | Bicyclooxyaryl thioureas and process for preparation | UNION CARBIDE CORPORATION (US) | 1984-11-07 | — | — | EP | claimed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0124282-B1 | BICYCLOOXYARYL THIOUREAS AND PROCESS FOR PREPARATION | UNION CARBIDE CORPORATION (US) | 1987-09-30 | — | — | EP | disclosed |
| US-4665097-A | Novel bicyclooxyaryl thioureas and process for preparation | UNION CARBIDE CORPORATION (US) | 1987-05-12 | — | — | US | disclosed |