Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10601673 | 0.89 | KMT2A (0.61) | KMT2AMEN1ATMMAPTUSP2 | |
| SCHEMBL8657856 | 0.85 | KMT2A (0.59) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10848987 | 0.84 | KMT2A (0.73) | KMT2AMEN1ATMMAPTUSP2 | |
| SCHEMBL8656132 | 0.83 | NPC1 (0.59) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10347947 | 0.83 | KMT2A (0.67) | KMT2AMEN1RAB9ANPC1ATM | |
| SCHEMBL8658188 | 0.83 | MEN1 (0.56) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL28098740 | 0.82 | ATM (0.68) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10918824 | 0.81 | KMT2A (0.73) | KMT2AMEN1ATMMAPTUSP2 | |
| SCHEMBL19707984 | 0.81 | KMT2A (0.66) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL10711197 | 0.81 | MEN1 (0.55) | KMT2AMEN1RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59106454-A | — | — | None | — | — | JP | disclosed |
| JP-58148847-A | — | — | None | — | — | JP | disclosed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| US-4564639-A | INSECTICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0088343-B1 | UREA DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| JP-S59106454-A | NOVEL UREA DERIVATIVE, ITS PREPARATION AND INSECTICIDAL COMPOSITION | TAKEDA CHEM IND LTD | 1984-06-20 | — | — | JP | disclosed |
| EP-0088343-A2 | Urea derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1983-09-14 | — | — | EP | disclosed |
| JP-S58148847-A | NOVEL UREA DERIVATIVE, ITS PREPARATION AND INSECTICIDAL COMPOSITION | TAKEDA CHEM IND LTD | 1983-09-05 | — | — | JP | disclosed |