Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | LMNA | P02545 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657856 | 0.85 | KMT2A (0.59) | NPC1LMNARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL8660904 | 0.83 | KMT2A (0.64) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8658188 | 0.83 | MEN1 (0.56) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9738032 | 0.83 | KMT2A (0.56) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28098740 | 0.82 | ATM (0.68) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10522150 | 0.81 | MEN1 (0.53) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL7605886 | 0.81 | KMT2A (0.59) | NPC1LMNARAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL352658 | 0.81 | MEN1 (0.54) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL29608194 | 0.81 | MEN1 (0.54) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL5311223 | 0.81 | ATM (0.56) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| US-4734436-A | LARVICIDES | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1988-03-29 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| US-4564639-A | INSECTICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-01-14 | — | — | US | disclosed |
| EP-0088343-B1 | UREA DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |