Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESRRA | P11474 | 5/20 | 0.58 |
| ▸ | GCGR | P47871 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | PYGL | P06737 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.47 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.47 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PARG | Q86W56 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10811580 | 0.90 | ESRRA (0.56) | ESRRANPC1RAB9AMEN1KMT2A | |
| SCHEMBL8660859 | 0.89 | ESRRA (0.53) | ESRRAGCGRNPC1RAB9APOLB | |
| SCHEMBL10963721 | 0.88 | ESRRA (0.54) | ESRRAGCGRNPC1RAB9APOLB | |
| SCHEMBL8659920 | 0.85 | ESRRA (0.51) | ESRRAGCGRNPC1RAB9APOLB | |
| SCHEMBL10964570 | 0.85 | GCGR (0.55) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8657606 | 0.85 | ESRRA (0.53) | ESRRANPC1RAB9APKMTDP1 | |
| SCHEMBL8655821 | 0.84 | GCGR (0.58) | ESRRAGCGRNPC1RAB9APOLB | |
| SCHEMBL11303176 | 0.82 | GCGR (0.59) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8660988 | 0.81 | GCGR (0.55) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8659992 | 0.81 | ESRRA (0.47) | ESRRAGCGRNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050321-B1 | NOVEL BICYCLOOXYPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND PESTICIDES CONTAINING THEM | UNION CARBIDE CORPORATION (US) | 1985-08-21 | — | — | EP | claimed |
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | claimed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | claimed |
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0050321-B1 | NOVEL BICYCLOOXYPHENYL UREAS, PROCESS FOR THEIR PREPARATION AND PESTICIDES CONTAINING THEM | UNION CARBIDE CORPORATION (US) | 1985-08-21 | — | — | EP | disclosed |
| EP-0124283-A1 | Process for the preparation of benzoyl ureas | UNION CARBIDE CORPORATION (US) | 1984-11-07 | — | — | EP | disclosed |
| US-4426385-A | Insecticidal bicyclooxyphenyl ureas | UNION CARBIDE CORPORATION (US) | 1984-01-17 | — | — | US | disclosed |
| EP-0050321-A2 | Novel bicyclooxyphenyl ureas, process for their preparation and pesticides containing them | UNION CARBIDE CORPORATION (US) | 1982-04-28 | — | — | EP | disclosed |