Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLN | Q9BYT8 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MECP2 | P51608 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664868 | 1.00 | NLN (0.61) | NLNTDP1POLBMAPTTP53 | |
| SCHEMBL8661069 | 1.00 | NLN (0.61) | NLNTDP1POLBMAPTTP53 | |
| 8-Aminoquinoline SCHEMBL8661890 | 0.94 | NLN (0.56) | NLNTDP1POLBMAPTTP53 | |
| 8-Aminoquinoline SCHEMBL8661892 | 0.94 | NLN (0.56) | NLNTDP1POLBMAPTTP53 | |
| SCHEMBL28252022 | 0.87 | NLN (0.64) | NLNTDP1POLBMAPTTP53 | |
| SCHEMBL28252023 | 0.87 | NLN (0.64) | NLNTDP1POLBMAPTTP53 | |
| SCHEMBL28750660 | 0.83 | TDP1 (0.63) | NLNTDP1POLBMAPTTP53 | |
| SCHEMBL28750659 | 0.83 | TDP1 (0.63) | NLNTDP1POLBMAPTTP53 | |
| SCHEMBL29152858 | 0.82 | SLC40A1 (0.70) | TDP1POLBMAPTTP53MEN1 | |
| SCHEMBL2323091 | 0.79 | ANPEP (0.62) | POLBMAPTSMN1; SMN2CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5804400-A | Electrochemiluminescent assay | IGEN INTERNATIONAL, INC. (US) | 1998-09-08 | — | — | US | disclosed |
| WO-1997028275-A1 | ELECTROCHEMILUMINESCENCE ENZYME ASSAY | IGEN INTERNATIONAL, INC. (US) | 1997-08-07 | — | — | WO | disclosed |