SCHEMBL8661899

SCHEMBL8661899

O=C(/C=C/C(=O)OCCC(O)O)OCCC(O)O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.48
HCAR2 Q8TDS4 7/20 0.45
LMNA P02545 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MAPT P10636 1/20 0.36
RAB9A P51151 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 4/20 0.34
ALDH1A1 P00352 3/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CHRNB2 P17787 3/20 0.33
CHRNA4 P43681 3/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
AKR1B10 O60218 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2488159 1.00 ATM (0.48) ATMHCAR2LMNATDP1MAPT
SCHEMBL8661909 0.91 HCAR2 (0.59) ATMHCAR2LMNATDP1MAPT
SCHEMBL27550205 0.91 HCAR2 (0.59) ATMHCAR2LMNATDP1MAPT
SCHEMBL25422020 0.91 HCAR2 (0.59) ATMHCAR2LMNATDP1MAPT
SCHEMBL10426089 0.86 ATM (0.56) ATMHCAR2LMNATDP1MAPT
SCHEMBL10396416 0.86 ATM (0.56) ATMHCAR2LMNATDP1MAPT
SCHEMBL29185576 0.81 ATM (0.45) ATMHCAR2LMNATDP1MAPT
SCHEMBL996461 0.81 TSHR (0.58) ATMTDP1TSHRALDH1A1TP53
SCHEMBL2814900 0.81 ATM (0.50) ATMHCAR2LMNATDP1MAPT
SCHEMBL2812263 0.81 ATM (0.50) ATMHCAR2LMNATDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12090254-B2 Composite tubular material prepared from extracellular matrix and synthetic polymer, and preparation method thereof NANKAI UNIVERSITY (CN) 2024-09-17 US claimed
US-20240024539-A1 COMPOSITE TUBULAR MATERIAL PREPARED FROM EXTRACELLULAR MATRIX AND SYNTHETIC POLYMER, AND PREPARATION METHOD THEREOF UNIV NANKAI (CN) 2024-01-25 US claimed
CN-113336929-B Degradable photocrosslinking triblock copolymer and preparation method and application thereof 中山大学 2023-07-11 CN claimed
WO-2023104096-A1 POROUS MICROCARRIER AND PREPARATION METHOD THEREFOR 中科睿极(深圳)医学科技有限公司 2023-06-15 WO claimed
CN-115011542-A Porous microcarrier and preparation method thereof 中科睿极(深圳)医学科技有限公司 2022-09-06 CN claimed
CN-114949365-A Extracellular matrix and synthetic polymer composite tubular material and preparation method thereof 南开大学 2022-08-30 CN claimed
CN-113150522-B Modified flame-retardant polyester material containing all-bio-based flame retardant and preparation method thereof 江南大学 2022-07-05 CN claimed
CN-114381092-A High-temperature thickening vinyl resin and preparation method thereof 江苏博泓新材料科技有限公司 2022-04-22 CN claimed
CN-111150888-B Double-effect film and preparation method thereof 财团法人工业技术研究院 2022-03-15 CN claimed
CN-110396293-B Easily-formed three-layer core-shell particle toughened polymer composite material and preparation method thereof 江南大学 2021-10-08 CN claimed
CN-110437581-B Multilayer core-shell particle toughened polymer composite material and preparation method thereof 江南大学 2021-09-28 CN claimed
CN-113150522-A Modified flame-retardant polyester material containing all-bio-based flame retardant and preparation method thereof 江南大学 2021-07-23 CN claimed
CN-110437580-B Bio-based core-shell particle toughened polymer composite material and preparation method thereof 江南大学 2020-10-09 CN claimed
CN-110423434-B Three-layer functionalized core-shell particle toughened polymer composite material and preparation method thereof 江南大学 2020-06-26 CN claimed
CN-111150888-A Double-effect film and preparation method thereof 财团法人工业技术研究院 2020-05-15 CN claimed
CN-119875027-A Polyester resin containing photoreactive dopamine and preparation method and application thereof 中山大学 2025-04-25 CN disclosed
US-12090254-B2 Composite tubular material prepared from extracellular matrix and synthetic polymer, and preparation method thereof NANKAI UNIVERSITY (CN) 2024-09-17 US disclosed
CN-111150888-A Double-effect film and preparation method thereof 财团法人工业技术研究院 2020-05-15 CN disclosed
US-5733951-A ESTER INTERCHANGE OF BIS/HYDROXYPROPYL/ FUMARATE WM. MARSH RICE UNIVERSITY 1998-03-31 US disclosed
WO-1995029710-A1 POLY(PROPYLENE FUMARATE) RICE UNIVERSITY (US) 1995-11-09 WO disclosed