Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 13/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27550205 | 1.00 | HCAR2 (0.59) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL25422020 | 1.00 | HCAR2 (0.59) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL8661899 | 0.91 | ATM (0.48) | HCAR2ATMTSHRTP53LMNA | |
| SCHEMBL2488159 | 0.91 | ATM (0.48) | HCAR2ATMTSHRTP53LMNA | |
| SCHEMBL10396418 | 0.88 | HCAR2 (0.61) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL2812266 | 0.84 | HCAR2 (0.60) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL2812265 | 0.84 | HCAR2 (0.60) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL29185581 | 0.84 | HCAR2 (0.55) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL2814903 | 0.84 | HCAR2 (0.60) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL28635181 | 0.82 | HCAR2 (0.53) | HCAR2ATMTSHRTP53EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5733951-A | ESTER INTERCHANGE OF BIS/HYDROXYPROPYL/ FUMARATE | WM. MARSH RICE UNIVERSITY | 1998-03-31 | — | — | US | disclosed |
| WO-1995029710-A1 | POLY(PROPYLENE FUMARATE) | RICE UNIVERSITY (US) | 1995-11-09 | — | — | WO | disclosed |
| US-4956421-A | COPOLYMERIZATION OF UNSATURATED ACIDS WITH ALKYLENE OXIDES IN THE PRESENCE OF A THIOETHER OR MERCAPTAN CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1990-09-11 | — | — | US | disclosed |
| US-4925905-A | DETERGENT ADDITIVES, MOLECULAR WEIGHT CONTROL | BASF AKTIENGESELLSCHAFT (DE) | 1990-05-15 | — | — | US | disclosed |
| US-4814102-A | Detergents containing oxyalkylated, carboxyl-containing polymers | BASF AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |