SCHEMBL8661920

SCHEMBL8661920

ClC(Cl)=CCOc1cc(Cl)c(OCCCCCCc2ccccc2)c(Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 3/20 0.41
S1PR3 Q99500 2/20 0.41
HPGD P15428 3/20 0.40
FFAR1 O14842 1/20 0.39
PLA2G4B P0C869 1/20 0.38
NAAA Q02083 1/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
S1PR5 Q9H228 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8658519 1.00 S1PR1 (0.41) S1PR1S1PR3HPGDFFAR1PLA2G4B
SCHEMBL8405678 0.99 S1PR1 (0.41) S1PR1S1PR3HPGDFFAR1PLA2G4B
SCHEMBL8660296 0.95 HPGD (0.39) S1PR1S1PR3HPGDFFAR1L3MBTL1
SCHEMBL8519414 0.91 HPGD (0.38) HPGDFFAR1
SCHEMBL8659576 0.91 MRGPRX4 (0.38) S1PR1S1PR3HPGDFFAR1L3MBTL1
SCHEMBL8408013 0.89 IGF1R (0.39) S1PR1S1PR3HPGDFFAR1L3MBTL1
SCHEMBL8658987 0.86 PPARA (0.39) S1PR1S1PR3CNR1CNR2
SCHEMBL8657406 0.86 RHEB (0.43) S1PR1FFAR1PLA2G4BNAAAL3MBTL1
SCHEMBL8405813 0.86 SCN8A (0.36) FFAR1
SCHEMBL8408754 0.85 HTT (0.39) S1PR1S1PR3HPGDL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed