Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664623 | 0.95 | HTR1D (0.64) | HTR1DHTR1B | |
| SCHEMBL8411444 | 0.91 | HTR1D (0.62) | HTR1DHTR1B | |
| SCHEMBL8699651 | 0.90 | HTR1D (0.64) | HTR1DHTR1B | |
| SCHEMBL8411688 | 0.88 | HTR1D (0.63) | HTR1DHTR1B | |
| SCHEMBL8410890 | 0.88 | HTR1D (0.62) | HTR1DHTR1B | |
| SCHEMBL8664209 | 0.87 | HTR1D (0.56) | HTR1DHTR1B | |
| SCHEMBL8413947 | 0.85 | HTR1D (0.64) | HTR1DHTR1B | |
| SCHEMBL8660434 | 0.85 | HTR1D (0.66) | HTR1DHTR1B | |
| SCHEMBL8414669 | 0.83 | HTR1D (0.63) | HTR1DHTR1B | |
| SCHEMBL8412878 | 0.83 | HTR1D (0.55) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807857-A | Piperazine, piperidine and tetrahydropyridine derivative of indol-3-alkyl as 5-HT1D-α agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-09-15 | — | — | US | disclosed |