Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8660733 | 0.86 | HTR1D (0.70) | HTR1DHTR1B | |
| SCHEMBL8662066 | 0.83 | HTR1D (0.83) | HTR1DHTR1B | |
| SCHEMBL7478079 | 0.80 | HTR1D (0.82) | HTR1DHTR1B | |
| SCHEMBL7475520 | 0.79 | HTR1D (0.84) | HTR1DHTR1B | |
| SCHEMBL8661963 | 0.78 | HTR1D (0.58) | HTR1DHTR1B | |
| SCHEMBL7804051 | 0.78 | HTR1D (0.73) | HTR1DHTR1B | |
| SCHEMBL8660677 | 0.75 | HTR1D (0.56) | HTR1DHTR1B | |
| SCHEMBL27700473 | 0.75 | HTR1D (0.60) | HTR1DHTR1B | |
| SCHEMBL8657524 | 0.75 | HTR1D (1.00) | HTR1DHTR1B | |
| SCHEMBL7808656 | 0.75 | GABRP (0.65) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807857-A | Piperazine, piperidine and tetrahydropyridine derivative of indol-3-alkyl as 5-HT1D-α agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-09-15 | — | — | US | disclosed |