Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | PLG | P00747 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19732818 | 0.80 | — | — | |
| SCHEMBL27966662 | 0.77 | EPHX1 (0.52) | ALOX15KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL21122034 | 0.77 | EPHX1 (0.52) | ALOX15KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL27150348 | 0.77 | EPHX1 (0.52) | ALOX15KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL9539874 | 0.77 | EPHX1 (0.52) | ALOX15KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL28041964 | 0.77 | EPHX1 (0.52) | ALOX15KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL13731861 | 0.77 | EPHX1 (0.52) | ALOX15KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL2420545 | 0.77 | EPHX1 (0.52) | ALOX15KMT2AMEN1ALDH1A1TSHR | |
| SCHEMBL28167200 | 0.77 | CA12 (0.50) | PAOXMAOAMAOBLMNAALOX15 | |
| SCHEMBL7004889 | 0.76 | PAOX (0.64) | PAOXMAOAMAOBLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514087-B1 | Polyphenylene ether-EPDM compositions | GEN ELECTRIC (US) | 1998-11-25 | — | — | EP | claimed |
| US-5258455-A | High strength, acyl funcionalized, low and high molecular weight | GENERAL ELECTRIC COMPANY (US) | 1993-11-02 | — | — | US | claimed |
| EP-2868676-A1 | Functionalised copolymer rubber containing nitrile groups | LANXESS Deutschland GmbH (DE) | 2015-05-06 | — | — | EP | disclosed |
| EP-2868677-A1 | Copolymer rubber containing nitrile groups | LANXESS Deutschland GmbH (DE) | 2015-05-06 | — | — | EP | disclosed |
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | AUSPEX PHARMACEUTICALS, INC. (US) | 2014-04-17 | — | — | US | disclosed |
| US-5258455-A | High strength, acyl funcionalized, low and high molecular weight | GENERAL ELECTRIC COMPANY (US) | 1993-11-02 | — | — | US | disclosed |
| US-5258455-A | High strength, acyl funcionalized, low and high molecular weight | GENERAL ELECTRIC COMPANY (US) | 1993-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107135-A1 | PYRIMIDINONE INHIBITORS OF LIPOPROTEIN-ASSOCIATED PHOSPHOLIPASE A2 | PLA2G1B, PLA2G4A, PLA2G4B | PAOX 277/4885MAOA 686/4885MAOB 684/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.