Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8662249 | 0.99 | HTT (0.46) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8665739 | 0.87 | HTT (0.61) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8664180 | 0.86 | HTT (0.48) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8662055 | 0.83 | POLB (0.43) | NPC1NPSR1POLBGAA | |
| SCHEMBL9700018 | 0.82 | HTT (0.53) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL8663227 | 0.82 | HTT (0.55) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL30887389 | 0.81 | HTT (0.58) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8662185 | 0.81 | HTT (0.54) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9475974 | 0.80 | HTT (0.53) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL9476339 | 0.80 | HTT (0.53) | HTTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619808-B1 | 3-HYDROXYPYRIDIN-4-ONE DERIVATIVES AS CHELATING AGENTS | BTG INT LTD (GB) | 1998-11-25 | — | — | EP | disclosed |
| US-5480894-A | 3-hydroxypyridin-4-one derivatives as chelating agents | BRITISH TECHNOLOGY GROUP LIMITED (GB) | 1996-01-02 | — | — | US | disclosed |