Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.36 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27456767 | 1.00 | MAPK14 (0.42) | MAPK14CA2MAOAMAOBCCNK | |
| SCHEMBL26428754 | 0.89 | MAPK14 (0.46) | MAPK14CA2CCNKCDK12 | |
| SCHEMBL1587316 | 0.85 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL1587319 | 0.85 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL7768997 | 0.84 | MAPK14 (0.41) | MAPK14CA2CCNKCDK12JAK2 | |
| SCHEMBL7768526 | 0.84 | MAPK14 (0.38) | MAPK14CCNKCDK12JAK2NTRK1 | |
| SCHEMBL5467053 | 0.82 | MAPK14 (0.44) | MAPK14 | |
| SCHEMBL22056912 | 0.82 | MAPK14 (0.50) | MAPK14CA2CCNKCDK12 | |
| SCHEMBL1684530 | 0.79 | RAB9A (0.45) | MAPK14 | |
| SCHEMBL1684533 | 0.79 | RAB9A (0.45) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5830920-A | PREVENTION GROWTH OF SMOOTH MUSCLE CELLS | HOFFMANN-LA ROCHE INC. (US) | 1998-11-03 | — | — | US | disclosed |