Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.59 |
| ▸ | MEN1 | O00255 | 8/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662287 | 1.00 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8645016 | 0.91 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8645013 | 0.91 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL10538827 | 0.91 | MAPT (0.63) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL10554800 | 0.90 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL10554790 | 0.90 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| Bromide SCHEMBL9075329 | 0.90 | MAPT (0.62) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| Bromide SCHEMBL9075332 | 0.90 | MAPT (0.62) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL8647744 | 0.88 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL10418508 | 0.88 | MAPT (0.59) | MAPTMEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789598-A | SEPARATING CARBONATE BY-PRODUCT; NEUTRALIZATION | TOKUYAMA CORPORATION (JP) | 1998-08-04 | — | — | US | disclosed |
| EP-0781769-A1 | Process for production of alkoxycarbonylaminothiazole acetic acid derivative | TOKUYAMA CORPORATION (JP) | 1997-07-02 | — | — | EP | disclosed |