SCHEMBL8662285

SCHEMBL8662285

CC(O)CCc1ccccn1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.53
ALDH1A1 P00352 3/20 0.53
CYP2C19 P33261 2/20 0.53
HRH1 P35367 2/20 0.52
HRH3 Q9Y5N1 1/20 0.52
LMNA P02545 2/20 0.50
TAAR1 Q96RJ0 1/20 0.50
ALOX15 P16050 1/20 0.50
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PTPRA P18433 1/20 0.47
TSHR P16473 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.44
HPGD P15428 1/20 0.44
KMT2A Q03164 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22420959 0.89 HRH1 (0.51) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL22420954 0.89 HRH1 (0.51) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL1856670 0.86 HRH1 (0.57) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL30201139 0.84 CYP1A2 (0.61) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL574013 0.84 CYP1A2 (0.61) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL19193695 0.81 CYP1A2 (0.50) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL20099801 0.81 CYP1A2 (0.50) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL6577893 0.81 HRH3 (0.49) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL6938906 0.81 HRH1 (0.57) CYP1A2ALDH1A1CYP2C19HRH1HRH3
SCHEMBL10771160 0.81 HRH1 (0.57) CYP1A2ALDH1A1CYP2C19HRH1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5518860-A IMPROVED ADHESION TO SILICON OXIDE AND NITRIDE SUBSTRATES TOKYO OHKA KOGYO CO., LTD. (JP) 1996-05-21 US claimed
CN-119431313-A Antifungal compound, preparation method and application thereof 上海交通大学 2025-02-14 CN disclosed
EP-3315492-A1 PYRAZOLE DERIVATIVE, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Kissei Pharmaceutical Co., Ltd. (JP) 2018-05-02 EP disclosed
US-5763461-A ANTIPICORNAVIRAL AGENTS SANOFI (FR) 1998-06-09 US disclosed
US-5618821-A VIRICIDES, PICORNAVIRUS SANOFI, S.A. (FR) 1997-04-08 US disclosed
WO-1995031438-A1 THERAPEUTIC PHENOXYALKYLHETEROCYCLES SANOFI WINTHROP, INC. (US) 1995-11-23 WO disclosed
US-5149698-A Pyrimidinyl alkyleneoxy bronchodilator agent GLAXO GROUP LIMITED (GB) 1992-09-22 US disclosed
US-4996218-A Bronchodilator, antiulcer agent, cardiovascular disorders GLAXO GROUP LIMITED (GB) 1991-02-26 US disclosed
EP-0303464-A2 Chloroaniline derivatives GLAXO GROUP LIMITED (GB) 1989-02-15 EP disclosed