SCHEMBL20099801

SCHEMBL20099801

C[C@H](CO)CCc1ccccn1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.50
ALDH1A1 P00352 3/20 0.50
CYP2C19 P33261 2/20 0.50
HRH3 Q9Y5N1 1/20 0.49
HRH1 P35367 2/20 0.48
LMNA P02545 2/20 0.47
TAAR1 Q96RJ0 1/20 0.47
ALOX15 P16050 1/20 0.47
KDM4E B2RXH2 1/20 0.47
TSHR P16473 1/20 0.47
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
TAS1R3 Q7RTX0 2/20 0.42
TAS1R1 Q7RTX1 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
CYP3A4 P08684 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18098078 0.84 CYP1A2 (0.51) CYP1A2ALDH1A1CYP2C19HRH3HRH1
Hydrochloric Acid SCHEMBL30593945 0.82 ALDH1A1 (0.51) CYP1A2ALDH1A1CYP2C19HRH3HRH1
SCHEMBL19185671 0.82 CYP1A2 (0.50) CYP1A2ALDH1A1CYP2C19HRH3HRH1
SCHEMBL15594566 0.81 FDPS (0.51) CYP1A2ALDH1A1CYP2C19HRH3HRH1
SCHEMBL8662285 0.81 CYP1A2 (0.53) CYP1A2ALDH1A1CYP2C19HRH3HRH1
SCHEMBL574013 0.81 CYP1A2 (0.61) CYP1A2ALDH1A1CYP2C19HRH3HRH1
SCHEMBL30201139 0.81 CYP1A2 (0.61) CYP1A2ALDH1A1CYP2C19HRH3HRH1
Hydrochloric Acid SCHEMBL28100597 0.81 ALDH1A1 (0.50) CYP1A2ALDH1A1CYP2C19HRH3HRH1
SCHEMBL22421032 0.80 HRH1 (0.50) CYP1A2ALDH1A1CYP2C19HRH3HRH1
SCHEMBL20333047 0.80 HRH1 (0.50) CYP1A2ALDH1A1CYP2C19HRH3HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3315492-A1 PYRAZOLE DERIVATIVE, OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF Kissei Pharmaceutical Co., Ltd. (JP) 2018-05-02 EP disclosed