Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KIT | P10721 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663363 | 0.90 | MAPT (0.51) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7350120 | 0.87 | MAPT (0.51) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL24670765 | 0.86 | KMT2A (0.60) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL7413531 | 0.86 | MAPT (0.53) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8661753 | 0.86 | MAPT (0.59) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8664298 | 0.86 | MAPT (0.59) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8462423 | 0.85 | MAPT (0.47) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8340167 | 0.85 | MAPT (0.49) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8321803 | 0.83 | HDAC8 (0.41) | MAPTSMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL8321062 | 0.83 | KIT (0.48) | MAPTKMT2AKITF10ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |