Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KIT | P10721 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462423 | 0.93 | MAPT (0.47) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8662409 | 0.90 | MAPT (0.54) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8662814 | 0.89 | BCL2 (0.50) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8664948 | 0.86 | TP53 (0.48) | MAPTSMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL8660500 | 0.85 | KIT (0.49) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7350120 | 0.84 | MAPT (0.51) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL24670765 | 0.84 | KMT2A (0.60) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL12814098 | 0.84 | NPSR1 (0.55) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL8468356 | 0.84 | MAPT (0.40) | MAPTSMN1; SMN2LMNAKMT2AMEN1 | |
| SCHEMBL7413531 | 0.84 | MAPT (0.53) | MAPTSMN1; SMN2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854245-A | Fibrinogen receptor antagonists | MERCK & CO., INC. (US) | 1998-12-29 | — | — | US | disclosed |