⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11586289 | 0.83 | MEN1 (0.34) | — | |
| SCHEMBL4911549 | 0.65 | MEN1 (0.47) | — | |
| SCHEMBL299115 | 0.65 | ALDH1A1 (0.47) | — | |
| SCHEMBL8663010 | 0.62 | — | — | |
| SCHEMBL31533679 | 0.62 | — | — | |
| SCHEMBL63786 | 0.62 | — | — | |
| SCHEMBL2523345 | 0.62 | — | — | |
| SCHEMBL4749624 | 0.62 | — | — | |
| SCHEMBL9389984 | 0.62 | — | — | |
| SCHEMBL28758918 | 0.62 | ALDH1A1 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170066711-A1 | METHOD FOR PRODUCING AN ARENE WITH AN AROMATIC C-N BOND ORTHO TO AN AROMATIC C-O BOND | THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY (CA) | 2017-03-09 | — | — | US | disclosed |
| EP-2210892-A2 | Neurologically-active compounds | Prana Biotechnology Limited (AU) | 2010-07-28 | — | — | EP | disclosed |
| US-20100160346-A1 | NEUROLOGICALLY ACTIVE COMPOUNDS | PRANA BIOTECHNOLOGY LIMITED (AU) | 2010-06-24 | — | — | US | disclosed |
| US-7692011-B2 | 8-hydroxy and 8-mercapto quinazolinones | PRANA BIOTECHNOLOGY LIMITED (AU) | 2010-04-06 | — | — | US | disclosed |
| US-7692011-B2 | 8-hydroxy and 8-mercapto quinazolinones | PRANA BIOTECHNOLOGY LIMITED (AU) | 2010-04-06 | — | — | US | disclosed |
| US-5808154-A | Process for the production of an aromatic hydrazo compound | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0439585-B1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS | MAG GEORG MAYRHOFER & CO OHG (AT) | 1997-10-29 | — | — | EP | disclosed |
| EP-0391606-B1 | Process for the production of an aromatic hydrazo compound | TOYO INK MFG CO (JP) | 1995-07-05 | — | — | EP | disclosed |
| US-5196478-A | Polystyrene, assays | EPIPHARM ALLERGIE-SERVICE GESELLSCHAFT M.B.H. (AT) | 1993-03-23 | — | — | US | disclosed |
| EP-0439585-A1 | IMMOBILISATION OF LIGANDS BY RADIO-DERIVATIZED POLYMERS. | EPIPHARM ALLERGIE SERVICE (AT) | 1991-08-07 | — | — | EP | disclosed |
| EP-0199436-B1 | COBALT(II) CHELATES AS CHAIN TRANSFER AGENTS IN FREE RADICAL POLYMERIZATIONS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4870049-A | TRANSFER SHEET FOR THERMAL PRINTING | SHARP KABUSHIKI KAISHA (JP) | 1989-09-26 | — | — | US | disclosed |
| US-4694054-A | MOLECULAR WEIGHT CONTROL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-09-15 | — | — | US | disclosed |
| US-4680352-A | Cobalt (II) chelates as chain transfer agents in free radical polymerizations | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-07-14 | — | — | US | disclosed |
| EP-0199436-A1 | Cobalt(II) chelates as chain transfer agents in free radical polymerizations | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-10-29 | — | — | EP | disclosed |
| EP-0196783-A1 | Cobalt(II) chelates as chain transfer agents in free radical polymerizations | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-10-08 | — | — | EP | disclosed |
| US-4608423-A | Linear addition polyester copolymers | SCM CORPORATION (US) | 1986-08-26 | — | — | US | disclosed |
| US-4547323-A | Synthesis of 2,2-dimethyl-4-methyleneglutaric acid and derivatives | SCM CORPORATION (US) | 1985-10-15 | — | — | US | disclosed |
| US-4526945-A | Copolymerizing methacrylic monomer or methacrylic and ethylenic monomers in the presence of free radical catalyst and cobalt glyoxime catalyst | SCM CORPORATION (US) | 1985-07-02 | — | — | US | disclosed |
| US-4513110-A | INCORPORATING RUBBER WITH DIKEVO COMPOUN IN WHICH THE KETO GROUPS ARE IN THE ORTHO POSITION IN A SIX MEMBERED CARBON RING | MONSANTO COMPANY (US) | 1985-04-23 | — | — | US | disclosed |