Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUT | P33316 | 2/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20037740 | 0.82 | DUT (0.37) | DUTL3MBTL1MAPTNFKB1KDM4E | |
| SCHEMBL23540665 | 0.82 | DUT (0.37) | DUTCYP11B1L3MBTL1MAPTNFKB1 | |
| SCHEMBL2462510 | 0.81 | CYP11B1 (0.36) | CYP11B1CYP11B2ALOX5APFEN1 | |
| SCHEMBL28999958 | 0.81 | DUT (0.36) | DUTCYP11B1CASP3SENP8SENP7 | |
| SCHEMBL30362904 | 0.81 | DUT (0.36) | DUTCYP11B1CASP3SENP8SENP7 | |
| SCHEMBL12143271 | 0.79 | S1PR4 (0.33) | — | |
| SCHEMBL20255383 | 0.78 | DUT (0.36) | DUTL3MBTL1MAPTKDM4EMEN1 | |
| SCHEMBL28316516 | 0.78 | CYP11B1 (0.38) | CYP11B1CYP11B2L3MBTL1MAPTNFKB1 | |
| SCHEMBL8662581 | 0.77 | CYP11B1 (0.32) | CYP11B1CYP11B2L3MBTL1MAPTNFKB1 | |
| SCHEMBL14183641 | 0.76 | KCNH2 (0.42) | DUTKDM4ELMNACYP1A2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |