Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662781 | 1.00 | TSHR (0.35) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL13783590 | 1.00 | TSHR (0.35) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL8776071 | 0.83 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL8377327 | 0.83 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL13702035 | 0.79 | TSHR (0.42) | TSHRHTR2CHTR2BKDM1A | |
| SCHEMBL16261738 | 0.79 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL16261737 | 0.79 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL782760 | 0.79 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL8377326 | 0.78 | TSHR (0.41) | TSHRHTR2CHTR2B | |
| SCHEMBL14719814 | 0.77 | TSHR (0.40) | TSHRTAAR1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5840728-A | VIRICIDES FOR TREATMENT OF HERPES VIRUS USING CYCLOPROPANATED CARBOCYCLIC 2*-DEOXYNUCLEOSIDE | UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-11-24 | — | — | US | disclosed |