Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8377327 | 1.00 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL8662781 | 0.83 | TSHR (0.35) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL8662773 | 0.83 | TSHR (0.35) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL13783590 | 0.83 | TSHR (0.35) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL782760 | 0.76 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL16261737 | 0.76 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL16261738 | 0.76 | TSHR (0.37) | TSHRTAAR1HTR2CHTR2BKDM1A | |
| SCHEMBL14719814 | 0.71 | TSHR (0.40) | TSHRTAAR1KDM1APDE4D | |
| SCHEMBL477836 | 0.70 | TAAR1 (0.41) | TSHRTAAR1 | |
| SCHEMBL4862979 | 0.69 | TSHR (0.38) | TSHRTAAR1HTR2BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0720604-B1 | CONFORMATIONALLY LOCKED NUCLEOSIDE ANALOGUES | US HEALTH (US) | 1997-11-19 | — | — | EP | disclosed |