SCHEMBL866282

SCHEMBL866282

Brc1ccc(N(c2ccc(Br)cc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.64
MAPK1 P28482 1/20 0.64
L3MBTL1 Q9Y468 3/20 0.50
TDP1 Q9NUW8 2/20 0.50
KDM4E B2RXH2 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
MAPT P10636 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
NPC1 O15118 1/20 0.45
NFKB1 P19838 1/20 0.45
RAB9A P51151 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
MEN1 O00255 1/20 0.42
CRHBP P24387 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1760565 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL19660645 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL13969320 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL403507 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL4237094 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL18533157 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL13969319 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL74527 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL20664596 1.00 ALDH1A1 (0.64) ALDH1A1MAPK1L3MBTL1TDP1KDM4E
SCHEMBL13854644 0.98 ALDH1A1 (0.68) ALDH1A1MAPK1L3MBTL1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8487055-B2 Hole transport polymers E I DU PONT DE NEMOURS AND COMPANY (US) 2013-07-16 US disclosed
US-8242223-B2 Polyarylamines, polyfluorenes, polycarbazoles; vapor deposition; electronics; semiconductors E I DU PONT DE NEMOURS AND COMPANY (US) 2012-08-14 US disclosed
US-20120077955-A1 HOLE TRANSPORT POLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2012-03-29 US disclosed
US-20080071049-A1 Polyarylamines, polyfluorenes, polycarbazoles; vapor deposition; electronics; semiconductors LG CHEM, LTD. (KR) 2008-03-20 US disclosed