Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.66 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.47 |
| ▸ | FEN1 | P39748 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661194 | 0.88 | PTGS2 (0.50) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8661267 | 0.88 | PTGS2 (0.64) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8663453 | 0.88 | PTGS2 (0.50) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8659078 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8660058 | 0.86 | PTGS2 (0.48) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8661210 | 0.86 | PTGS2 (0.55) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8659788 | 0.86 | PTGS2 (0.66) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8662931 | 0.85 | ALOX5AP (0.47) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8659455 | 0.85 | PTGS2 (0.54) | PTGS2PTGS1ALOX5APFEN1 | |
| SCHEMBL8659613 | 0.85 | ALOX5AP (0.56) | PTGS2PTGS1ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | claimed |
| US-5739166-A | ALKYLSULFONYL OR AMINOSULFONYL SUBSTITUTED AROMATIC COMPOUNDS AS NON-STEROIDAL ANTIINFLAMMATORY AGENT | G.D. SEARLE & CO. (US) | 1998-04-14 | — | — | US | disclosed |