Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.32 |
| ▸ | PPARG | P37231 | 6/20 | 0.32 |
| ▸ | PPARD | Q03181 | 6/20 | 0.32 |
| ▸ | PPARA | Q07869 | 6/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TLR2 | O60603 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15295443 | 0.88 | SIRT2 (0.41) | SIRT2 | |
| SCHEMBL8622095 | 0.85 | SIRT2 (0.45) | SIRT2PTPN1ACP1CDC25B | |
| SCHEMBL2765891 | 0.84 | DGAT1 (0.37) | TSHRALDH1A1 | |
| SCHEMBL4608849 | 0.84 | SIRT2 (0.39) | SIRT2 | |
| SCHEMBL5186468 | 0.84 | SIRT2 (0.39) | SIRT2 | |
| SCHEMBL8621156 | 0.83 | SIRT2 (0.47) | SIRT2PTPN1ACP1CDC25B | |
| SCHEMBL6079946 | 0.82 | DGAT1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL11218707 | 0.81 | SIRT2 (0.54) | SIRT2PTPN1ACP1CDC25B | |
| SCHEMBL6908218 | 0.81 | SIRT2 (0.54) | SIRT2PTPN1ACP1CDC25B | |
| SCHEMBL8622131 | 0.80 | SIRT2 (0.41) | SIRT2PTPN1ACP1CDC25BTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0878497-A2 | Fragrance precursor compounds | GIVAUDAN-ROURE (INTERNATIONAL) S.A. (CH) | 1998-11-18 | — | — | EP | claimed |