Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.38 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665836 | 1.00 | CYP2C9 (0.45) | CYP2C9CYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL9450648 | 1.00 | CYP2C9 (0.45) | CYP2C9CYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL4311579 | 0.91 | CYP2C9 (0.33) | CYP2C9CYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL21041435 | 0.88 | EPHX2 (0.45) | LMNAALDH1A1HPGDCYP3A4 | |
| SCHEMBL6169087 | 0.69 | HRH3 (0.47) | CYP2C9CYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL6051450 | 0.69 | — | — | |
| SCHEMBL2705800 | 0.68 | CYP2C9 (0.41) | CYP2C9CYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL8746707 | 0.68 | CYP2C9 (0.41) | CYP2C9CYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL6663301 | 0.66 | CYP2C9 (0.46) | CYP2C9CYP2C19SMN1; SMN2LMNAMAPT | |
| SCHEMBL1862375 | 0.66 | GPR84 (0.41) | GPR84G6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854174-A | Substantially non-photosensitive thermographic recording material with improved stability and image-tone | AGFA-GEVAERT (BE) | 1998-12-29 | — | — | US | disclosed |
| EP-0809143-A1 | Substantially non-photosensitive thermographic recording material with improved stability and image-tone | AGFA-GEVAERT N.V. (BE) | 1997-11-26 | — | — | EP | disclosed |