Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 8/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.33 |
| ▸ | BCHE | P06276 | 7/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13309507 | 0.82 | ALOX5 (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL31314432 | 0.82 | ALOX5 (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL1567962 | 0.82 | ALOX5 (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL29483920 | 0.82 | ALOX5 (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL11750965 | 0.82 | ALOX5 (0.41) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| Hydrochloric Acid SCHEMBL30892599 | 0.81 | ALOX5 (0.40) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL9279386 | 0.76 | PTGS1 (0.36) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL25015606 | 0.71 | PTGS1 (0.47) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL8649723 | 0.71 | PTGS1 (0.47) | PTGS1PTGS2CYP1A2CYP3A4TSHR | |
| SCHEMBL2059215 | 0.69 | PTGS1 (0.67) | PTGS1PTGS2CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0604995-B1 | Hydroxyamines N-acyl derivatives having scavenger activity and useful in acute and chronic pathologies associated with peroxidation and inflammation phenomena | LIFEGROUP SPA (IT) | 1998-09-30 | — | — | EP | disclosed |
| US-5480645-A | Hydroxyamines N-acyl derivatives having scavenger activity and useful in acute and chronic pathologies associated with peroxidation and inflammation phenomena | LIFEGROUP S.P.A. (IT) | 1996-01-02 | — | — | US | disclosed |
| EP-0604995-A1 | Hydroxyamines N-acyl derivatives having scavenger activity and useful in acute and chronic pathologies associated with peroxidation and inflammation phenomena | LIFEGROUP S.p.A. (IT) | 1994-07-06 | — | — | EP | disclosed |