SCHEMBL8663198

SCHEMBL8663198

C=C(C)C(=O)Oc1ccccc1OC(=O)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.48
ELANE P08246 1/20 0.43
LMNA P02545 2/20 0.37
KDM4E B2RXH2 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
SERPINE1 P05121 1/20 0.37
HTT P42858 3/20 0.35
TP53 P04637 2/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 3/20 0.35
ATM Q13315 2/20 0.35
MAPT P10636 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GAA P10253 1/20 0.34
ALDH1A1 P00352 1/20 0.34
ESR1 P03372 1/20 0.34
ITGB3 P05106 1/20 0.34
ITGA2B P08514 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30803748 0.82 ELANE (0.56) KMT2AELANELMNAKDM4EHSD17B10
SCHEMBL1232932 0.82 ELANE (0.56) KMT2AELANELMNAKDM4EHSD17B10
SCHEMBL30803750 0.82 ELANE (0.56) KMT2AELANELMNAKDM4EHSD17B10
SCHEMBL10234874 0.80 ALDH1A1 (0.35) KMT2AELANEMAPK1ATMALDH1A1
SCHEMBL2835587 0.78 KMT2A (0.47) KMT2AHTTTP53TDP1ATM
SCHEMBL28162293 0.78 ELANE (0.58) KMT2AELANELMNAKDM4EHSD17B10
SCHEMBL6903312 0.78 ELANE (0.49) KMT2AELANELMNAKDM4EHSD17B10
SCHEMBL2833913 0.78 KMT2A (0.54) KMT2ALMNASERPINE1HTTTP53
SCHEMBL8962026 0.77 ELANE (0.51) KMT2AELANELMNAKDM4EHSD17B10
SCHEMBL14173261 0.77 ELANE (0.51) KMT2AELANELMNAKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5769393-A Liquid crystal elements and method of producing same SEIKO EPSON CORPORATION (JP) 1998-06-23 US disclosed
EP-0563403-A1 DISPLAY ELEMENT AND ITS MANUFACTURING METHOD SEIKO EPSON CORPORATION (JP) 1993-10-06 EP disclosed