SCHEMBL8663291

SCHEMBL8663291

CN(c1cccc(O)c1)C1CCCCC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
TSHR P16473 1/20 0.53
TYR P14679 1/20 0.47
CYP3A4 P08684 1/20 0.44
OPRM1 P35372 7/20 0.43
SLC6A4 P31645 2/20 0.43
KDR P35968 1/20 0.43
SLC6A3 Q01959 1/20 0.43
HTR7 P34969 1/20 0.41
OPRD1 P41143 6/20 0.41
OPRK1 P41145 6/20 0.41
ESR1 P03372 1/20 0.40
MEN1 O00255 1/20 0.40
SLC6A2 P23975 1/20 0.40
KMT2A Q03164 1/20 0.40
POLB P06746 2/20 0.40
KDM4E B2RXH2 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
GFER P55789 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28643378 0.82 ALDH1A1 (0.47) ALDH1A1TSHRCYP3A4OPRM1SLC6A4
SCHEMBL10887293 0.81 POLB (0.49) ALDH1A1MEN1KMT2APOLBKDM4E
SCHEMBL1466290 0.79 CYP3A4 (0.37) ALDH1A1TYRCYP3A4MEN1KMT2A
SCHEMBL7070859 0.79 ALDH1A1 (0.53) ALDH1A1TSHRCYP3A4OPRM1HTR7
SCHEMBL11692239 0.79 POLB (0.47) MEN1KMT2APOLBNPC1RAB9A
Methyl Alcohol SCHEMBL9678518 0.78 KDM4E (0.47) ALDH1A1TSHRESR1MEN1KMT2A
SCHEMBL6872363 0.78 TYR (0.44) ALDH1A1TYRESR1MEN1KMT2A
SCHEMBL28653852 0.78 ALDH1A1 (0.50) ALDH1A1TSHRCYP3A4OPRM1HTR7
SCHEMBL19227252 0.77 ALDH1A1 (0.50) ALDH1A1TSHRESR1MEN1KMT2A
SCHEMBL20733138 0.77 ALDH1A1 (0.50) ALDH1A1TSHRESR1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109020827-B Method for synthesizing m-dialkylaminophenol 浙江山峪集团股份有限公司 2021-04-27 CN disclosed
CN-1084327-C Method for preparing amino-phenol CIBA SC HOLDING AG (CH) 2002-05-08 CN disclosed
CN-1178785-A Method for preparing amino-phenol CIBA GEIGY AG (CH) 1998-04-15 CN disclosed
US-5710335-A REACTING RESORCIN WITH PRIMARY AMINE THEN ALKYL HALIDE MITSUI TOATSU CHEMICALS, INC. (JP) 1998-01-20 US disclosed