SCHEMBL8663464

SCHEMBL8663464

C1=Cc2cc3c(cc2CC1)CCCC3

nearest known ligand 0.37

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 1/20 0.37
ALDH1A1 P00352 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
NOS3 P29474 1/20 0.30
NOS1 P29475 1/20 0.30
NOS2 P35228 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8661118 0.85
SCHEMBL31276725 0.79 CDC25B (0.38) CDC25BALDH1A1KDM4EMEN1GAA
SCHEMBL38659519 0.77 CDC25B (0.37) CDC25BALDH1A1KDM4EMEN1GAA
SCHEMBL8664024 0.76
SCHEMBL21879179 0.76 CDC25B (0.34) CDC25BALDH1A1KDM4EMEN1GAA
SCHEMBL2873870 0.76
SCHEMBL412114 0.74 CDC25B (0.33) CDC25B
SCHEMBL29767574 0.74 CDC25B (0.33) CDC25B
SCHEMBL21169966 0.73 ADCY6 (0.38) ALDH1A1KDM4EMEN1GAAMAPT
Lithium SCHEMBL29767632 0.73 CDC25B (0.32) CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5808154-A Process for the production of an aromatic hydrazo compound TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-15 US disclosed
EP-0391606-B1 Process for the production of an aromatic hydrazo compound TOYO INK MFG CO (JP) 1995-07-05 EP disclosed
EP-0391606-A1 Process for the production of an aromatic hydrazo compound TOYO INK MANUFACTURING CO., LTD. (JP) 1990-10-10 EP disclosed
EP-0193709-A3 SUBSTITUTED OCTAHYDROANTHRACENES AND PROCESS FOR THEIR PREPARATION HÜLS AKTIENGESELLSCHAFT (DE) 1988-08-03 EP disclosed
EP-0193709-A2 Substituted octahydroanthracenes and process for their preparation HÜLS AKTIENGESELLSCHAFT (DE) 1986-09-10 EP disclosed