Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 19/20 | 0.67 |
| ▸ | HTR1B | P28222 | 19/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8699649 | 0.93 | HTR1D (0.63) | HTR1DHTR1B | |
| SCHEMBL8662193 | 0.90 | HTR1D (0.64) | HTR1DHTR1B | |
| SCHEMBL8660677 | 0.90 | HTR1D (0.56) | HTR1DHTR1B | |
| SCHEMBL8662143 | 0.90 | HTR1D (0.63) | HTR1DHTR1B | |
| SCHEMBL8664130 | 0.89 | HTR1D (0.64) | HTR1DHTR1B | |
| SCHEMBL8664620 | 0.85 | HTR1D (0.61) | HTR1DHTR1B | |
| SCHEMBL8662445 | 0.85 | HTR1D (0.53) | HTR1DHTR1B | |
| SCHEMBL8662156 | 0.85 | HTR1D (0.65) | HTR1DHTR1B | |
| SCHEMBL8665362 | 0.85 | HTR1D (0.66) | HTR1DHTR1B | |
| SCHEMBL8662629 | 0.83 | HTR1D (0.64) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | claimed |
| US-5808064-A | HYDROSILATION OF AN INDOLE AS CHEMICAL INTERMEDIATE | MERCK & CO., INC. (US) | 1998-09-15 | — | — | US | disclosed |
| US-5807857-A | Piperazine, piperidine and tetrahydropyridine derivative of indol-3-alkyl as 5-HT1D-α agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-09-15 | — | — | US | disclosed |