SCHEMBL8663547

SCHEMBL8663547

O=C1C=C(Cl)c2c(Cl)cccc2C1=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 3/20 0.52
AURKA O14965 1/20 0.49
AURKB Q96GD4 1/20 0.49
KDM4E B2RXH2 3/20 0.47
MAPT P10636 3/20 0.47
POLB P06746 2/20 0.47
RECQL P46063 2/20 0.47
ATM Q13315 1/20 0.47
NSD2 O96028 3/20 0.42
PTPN1 P18031 3/20 0.41
CES1 P23141 3/20 0.40
BCHE P06276 1/20 0.40
DAO P14920 1/20 0.40
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
MAPK1 P28482 1/20 0.39
PTPN22 Q9Y2R2 1/20 0.39
HKDC1 Q2TB90 1/20 0.39
ADORA2A P29274 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30003334 0.84 AURKA (0.53) PTPRCAURKAAURKBKDM4EMAPT
SCHEMBL9627478 0.84 AURKA (0.53) PTPRCAURKAAURKBKDM4EMAPT
SCHEMBL125609 0.78 NSD2 (0.55) MAPTNSD2CES1BCHEDAO
SCHEMBL122441 0.76 NSD2 (0.62) KDM4EMAPTNSD2CES1BCHE
SCHEMBL2529860 0.74 PTPRC (0.59) PTPRCKDM4EMAPTPOLBRECQL
SCHEMBL4585020 0.73 NSD2 (0.55) PTPRCMAPTNSD2CES1BCHE
SCHEMBL23271685 0.73 MAPT (0.64) PTPRCAURKAAURKBKDM4EMAPT
SCHEMBL18992139 0.73 MAPT (0.53) PTPRCAURKAAURKBKDM4EMAPT
SCHEMBL29407083 0.73 MAPT (0.53) PTPRCAURKAAURKBKDM4EMAPT
SCHEMBL23271713 0.73 S100A4 (0.46) PTPRCAURKAAURKBKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5808154-A Process for the production of an aromatic hydrazo compound TOYO INK MANUFACTURING CO., LTD. (JP) 1998-09-15 US disclosed
EP-0391606-B1 Process for the production of an aromatic hydrazo compound TOYO INK MFG CO (JP) 1995-07-05 EP disclosed
EP-0391606-A1 Process for the production of an aromatic hydrazo compound TOYO INK MANUFACTURING CO., LTD. (JP) 1990-10-10 EP disclosed