Butanone

Butanone

SCHEMBL8663620

C=CC(C)=O.CCC(C)=O

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.69
TDP1 Q9NUW8 4/20 0.62
TSHR P16473 7/20 0.55
FFAR3 O14843 1/20 0.37
TP53 P04637 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.36
FGFR4 P22455 1/20 0.35
TRPA1 O75762 1/20 0.35
MAPK1 P28482 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
THRB P10828 2/20 0.31
THRA P10827 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid SCHEMBL10543499 0.85 ALDH1A1 (0.59) ALDH1A1TDP1TSHRFFAR3TP53
Butanone SCHEMBL28437516 0.84
Butanone SCHEMBL8207534 0.84
SCHEMBL5145577 0.83
SCHEMBL14964 0.83
Acrylamide SCHEMBL11529233 0.82 ALDH1A1 (0.61) ALDH1A1TDP1TSHRFFAR3TP53
Acrylamide SCHEMBL28200115 0.82 ALDH1A1 (0.61) ALDH1A1TDP1TSHRFFAR3TP53
Propionamide SCHEMBL4543816 0.82 ALDH1A1 (0.61) ALDH1A1TDP1TSHRFFAR3TP53
Butanone SCHEMBL9281749 0.81
SCHEMBL9410827 0.80 ALDH1A1 (0.79) ALDH1A1TDP1TSHRFFAR3TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0723981-B1 Process for manufacturing isoprene containing block copolymers SHELL INT RESEARCH (NL) 1998-12-09 EP disclosed
US-5736612-A ANIONIC BLOCK POLYMERIZATION VIA A LIVING POLYMER INITIATED WITH A MONOFUNCTIONAL ORGANOLITHIUM TO FORM A POLYSTYRENE SEGMENT, ADDING PRETREATED ISOPRENE CONCENTRATE TO FORM A POLYISOPRENE SEGMENT AND A COUPLING OR TERMINATING AGENT SHELL OIL COMPANY (US) 1998-04-07 US disclosed
EP-0723981-A1 Process for manufacturing isoprene containing block copolymers SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1996-07-31 EP disclosed