Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 7/20 | 0.49 |
| ▸ | CA1 | P00915 | 7/20 | 0.49 |
| ▸ | CA2 | P00918 | 7/20 | 0.49 |
| ▸ | CA9 | Q16790 | 7/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778062 | 0.96 | CA12 (0.53) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL8573230 | 0.84 | LMNA (0.53) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL19611819 | 0.84 | CA12 (0.45) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL5190368 | 0.83 | CA12 (0.64) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL29437100 | 0.83 | CA12 (0.64) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL6400413 | 0.83 | TTR (0.40) | CA12CA1CA2CA9POLB | |
| SCHEMBL8663705 | 0.79 | LMNA (0.51) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL16240781 | 0.79 | LMNA (0.42) | LMNAHTTCA12CA1CA2 | |
| SCHEMBL8654292 | 0.76 | CA1 (0.39) | HTTCA12CA1CA2CA9 | |
| SCHEMBL8406469 | 0.76 | LMNA (0.54) | LMNAHTTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5837670-A | AQUEOUS WASH LIQUOR COMPRISING ALKYL SULFATE SURFACTANT, SULFONATED PHTHALOCYANINE, AMIDE SUDS SUPPRESSOR | PROCTER & GAMBLE COMPANY, THE | 1998-11-17 | — | — | US | disclosed |