Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.54 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.54 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.54 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 8/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 2/20 | 0.40 |
| ▸ | PLK4 | O00444 | 2/20 | 0.40 |
| ▸ | DAPK3 | O43293 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | GSK3A | P49840 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | PRKX | P51817 | 2/20 | 0.40 |
| ▸ | CSNK1G2 | P78368 | 2/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | CDC42BPA | Q5VT25 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7886866 | 0.83 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8PLK1 | |
| SCHEMBL7886860 | 0.83 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8PLK1 | |
| SCHEMBL7894022 | 0.83 | ABCC9 (0.58) | ABCC9ABCC8KCNJ11KCNJ8PLK1 | |
| SCHEMBL7012005 | 0.80 | PLK1 (0.47) | PLK1CHEK1CDC7PLK4DAPK3 | |
| SCHEMBL7534843 | 0.77 | ABCC9 (0.54) | ABCC9ABCC8KCNJ11KCNJ8PLK1 | |
| SCHEMBL8372683 | 0.77 | PLK1 (0.67) | ABCC9ABCC8KCNJ11KCNJ8PLK1 | |
| SCHEMBL7347226 | 0.77 | PLK1 (0.67) | ABCC9ABCC8KCNJ11KCNJ8PLK1 | |
| SCHEMBL7895529 | 0.76 | EPHX2 (0.52) | ABCC9ABCC8KCNJ11KCNJ8PLK1 | |
| SCHEMBL8667527 | 0.74 | ABCC9 (0.51) | ABCC9ABCC8KCNJ11KCNJ8PLK1 | |
| SCHEMBL7536100 | 0.73 | ABCC9 (0.50) | ABCC9ABCC8KCNJ11KCNJ8PLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5846999-A | Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-08 | — | — | US | claimed |
| US-5846999-A | Substituted N-arylmethylamino derivatives of cyclobutene-3,4-diones | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-12-08 | — | — | US | disclosed |