⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2510886 | 0.62 | TSHR (0.33) | — | |
| SCHEMBL3408 | 0.59 | — | — | |
| SCHEMBL1475071 | 0.59 | — | — | |
| SCHEMBL446571 | 0.59 | — | — | |
| SCHEMBL437448 | 0.59 | — | — | |
| SCHEMBL5999784 | 0.58 | — | — | |
| Tert-Butanol SCHEMBL788666 | 0.57 | ALDH1A1 (0.46) | — | |
| Tert-Butanol SCHEMBL20503401 | 0.57 | ALDH1A1 (0.46) | — | |
| SCHEMBL39492 | 0.57 | — | — | |
| Tert-Butanol SCHEMBL282 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111777626-B | Venetian-dihydroartemisinin split compound and preparation and application thereof | 沈阳药科大学 | 2021-07-09 | — | — | CN | disclosed |
| US-10640526-B2 | Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2020-05-05 | — | — | US | disclosed |
| US-20180319833-A1 | Method of preparation of 6-azido-2,4-diacetamido-2,4,6-trideoxy-D-mannose | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2018-11-08 | — | — | US | disclosed |
| EP-3377508-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2018-09-26 | — | — | EP | disclosed |
| EP-3170832-A1 | METHOD OF PREPARATION OF 6-AZIDO-2,4-DIACETAMIDO-2,4,6-TRIDEOXY-D-MANNOSE | Centre National De La Recherche Scientifique (FR) | 2017-05-24 | — | — | EP | disclosed |
| US-5789408-A | Antiviral thiazoles | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| WO-1995005378-A1 | ANTIVIRAL THIAZOLES | PFIZER INC. (US) | 1995-02-23 | — | — | WO | disclosed |