Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 17/20 | 0.49 |
| ▸ | MMP3 | P08254 | 11/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.47 |
| ▸ | FCER2 | P06734 | 3/20 | 0.47 |
| ▸ | BMP1 | P13497 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6413230 | 0.90 | MMP3 (0.45) | MMP2MMP3MMP9FCER2MMP1 | |
| SCHEMBL8665728 | 0.89 | MMP3 (0.44) | MMP2MMP3MMP9FCER2MMP1 | |
| SCHEMBL8667836 | 0.89 | FCER2 (0.48) | MMP2MMP3MMP9FCER2MMP1 | |
| SCHEMBL6412000 | 0.87 | FCER2 (0.44) | MMP2MMP3MMP9FCER2BMP1 | |
| SCHEMBL7764984 | 0.87 | MMP3 (0.48) | MMP2MMP3MMP9FCER2MMP1 | |
| SCHEMBL6417772 | 0.87 | MMP3 (0.48) | MMP2MMP3MMP9FCER2MMP1 | |
| SCHEMBL7758553 | 0.87 | FCER2 (0.40) | MMP2MMP3MMP9FCER2MMP1 | |
| SCHEMBL6418840 | 0.87 | FCER2 (0.40) | MMP2MMP3MMP9FCER2MMP1 | |
| SCHEMBL8652782 | 0.80 | CYP2C9 (0.43) | MMP2MMP3MMP9FCER2MMP1 | |
| SCHEMBL8668754 | 0.79 | MMP3 (0.58) | MMP2MMP3MMP9MMP1MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0712390-B1 | SUCCINAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS GELATINASE AND COLLAGENASE INHIBITORS | CELLTECH THERAPEUTICS LTD (GB) | 1998-12-09 | — | — | EP | disclosed |
| WO-1995004033-A1 | SUCCINAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS GELATINASE AND COLLAGENASE INHIBITORS | CELLTECH LIMITED (GB) | 1995-02-09 | — | — | WO | disclosed |