Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 7/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8665627 | 0.92 | NPC1 (0.50) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL8664162 | 0.90 | NPC1 (0.51) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL8666250 | 0.89 | PTGER4 (0.54) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL8663180 | 0.88 | ALDH1A1 (0.47) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL8668173 | 0.86 | CSNK1D (0.49) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL8665353 | 0.83 | CSNK1D (0.59) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL8668026 | 0.82 | NPC1 (0.49) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL8664253 | 0.80 | SMN1; SMN2 (0.47) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL7543452 | 0.78 | NPC1 (0.58) | NPC1RAB9AMAPTALDH1A1MEN1 | |
| SCHEMBL8663798 | 0.78 | CSNK1D (0.49) | NPC1RAB9AMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5736487-A | HERBICIDES | SANKYO COMPANY, LIMITED (JP) | 1998-04-07 | — | — | US | disclosed |