Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL338384 | 0.68 | RPS6KA3 (0.52) | PNPRPS6KA3 | |
| SCHEMBL1276252 | 0.64 | PDPK1 (0.32) | — | |
| Leucopterin SCHEMBL12948394 | 0.63 | PNP (0.43) | PNPCYP3A4BLM | |
| SCHEMBL19002859 | 0.62 | PDPK1 (0.43) | PNPCYP3A4BLMRPS6KA3 | |
| SCHEMBL460884 | 0.60 | PNP (0.39) | PNPCYP3A4BLM | |
| Guanine SCHEMBL16389311 | 0.59 | PNP (0.44) | PNPCYP3A4BLM | |
| SCHEMBL9044197 | 0.59 | DYRK1A (0.53) | PNPCYP3A4BLM | |
| SCHEMBL21895447 | 0.58 | RPS6KA3 (0.37) | RPS6KA3 | |
| SCHEMBL22060804 | 0.58 | RPS6KA3 (0.37) | RPS6KA3 | |
| SCHEMBL17904270 | 0.58 | RPS6KA3 (0.37) | RPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636372-B1 | Antiviral, antitumor, antimetastatic, immune system enhancing 7-thia-guanosine derivatives | ICN PHARMACEUTICALS (US) | 1998-12-02 | — | — | EP | disclosed |
| EP-0348446-B1 | ANTIVIRAL ANTITUMOR ANTIMETASTATIC IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES | UNIV BRIGHAM YOUNG (US) | 1995-08-09 | — | — | EP | disclosed |
| EP-0636372-A1 | Antiviral, antitumor, antimetastatic, immune system enhancing 7-thia-guanosine derivatives | BRIGHAM YOUNG UNIVERSITY (US) | 1995-02-01 | — | — | EP | disclosed |
| EP-0348446-A4 | ANTIVIRAL ANTITUMOR ANTIMETASTATIC IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES | — | 1991-09-25 | — | — | EP | disclosed |
| US-5041426-A | Viricides, antitumor agents | BRIGHAM YOUNG UNIVERSITY (US) | 1991-08-20 | — | — | US | disclosed |
| EP-0348446-A1 | ANTIVIRAL ANTITUMOR ANTIMETASTATIC IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES. | UNIV BRIGHAM YOUNG (US) | 1990-01-03 | — | — | EP | disclosed |
| WO-1989005649-A1 | ANTIVIRAL ANTITUMOR ANTIMETASTATIC IMMUNE SYSTEM ENHANCING NUCLEOSIDES AND NUCLEOTIDES | BRIGHAM YOUNG UNIVERSITY (US) | 1989-06-29 | — | — | WO | disclosed |