Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11249699 | 1.00 | TSHR (0.46) | TSHRHIF1AFAAHTRPV1OXER1 | |
| SCHEMBL848730 | 1.00 | TSHR (0.46) | TSHRHIF1AFAAHTRPV1OXER1 | |
| SCHEMBL2486224 | 1.00 | TSHR (0.46) | TSHRHIF1AFAAHTRPV1OXER1 | |
| SCHEMBL835618 | 0.97 | HIF1A (0.47) | TSHRHIF1AFAAHTRPV1OXER1 | |
| SCHEMBL693531 | 0.89 | — | — | |
| SCHEMBL16104757 | 0.80 | TSHR (0.48) | TSHRHIF1AFAAHTRPV1ACLY | |
| SCHEMBL10546638 | 0.80 | TSHR (0.42) | TSHRHIF1AFAAHTRPV1 | |
| SCHEMBL848156 | 0.80 | TSHR (0.42) | TSHRHIF1AFAAHTRPV1 | |
| SCHEMBL19554091 | 0.80 | TSHR (0.42) | TSHRHIF1AFAAHTRPV1 | |
| SCHEMBL285606 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672686-B1 | GANGLIOSIDE GM3 DERIVATIVE HAVING FLUORINATED CERAMIDE MOIETY | DAIKIN IND LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5583208-A | Ganglioside GM3 derivatives containing fluorine in ceramide portion | DAIKIN INDUSTRIES, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0672686-A1 | GANGLIOSIDE GM3 DERIVATIVE HAVING FLUORINATED CERAMIDE MOIETY | DAIKIN INDUSTRIES, LIMITED (JP) | 1995-09-20 | — | — | EP | disclosed |