SCHEMBL835618

SCHEMBL835618

O=CCCCCC(F)(F)F

nearest known ligand 0.47

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 1/20 0.47
TSHR P16473 2/20 0.42
FAAH O00519 2/20 0.37
TRPV1 Q8NER1 2/20 0.37
OXER1 Q8TDS5 1/20 0.34
ALOX5 P09917 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8664329 0.97 TSHR (0.46) HIF1ATSHRFAAHTRPV1OXER1
SCHEMBL11249699 0.97 TSHR (0.46) HIF1ATSHRFAAHTRPV1OXER1
SCHEMBL848730 0.97 TSHR (0.46) HIF1ATSHRFAAHTRPV1OXER1
SCHEMBL2486224 0.97 TSHR (0.46) HIF1ATSHRFAAHTRPV1OXER1
SCHEMBL693531 0.92
SCHEMBL285606 0.79
SCHEMBL19554091 0.77 TSHR (0.42) HIF1ATSHRFAAHTRPV1
SCHEMBL10546638 0.77 TSHR (0.42) HIF1ATSHRFAAHTRPV1
SCHEMBL16104757 0.77 TSHR (0.48) HIF1ATSHRFAAHTRPV1ALDH1A1
SCHEMBL848156 0.77 TSHR (0.42) HIF1ATSHRFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME SENDA BIOSCIENCES INC (US) 2023-07-27 US disclosed
EP-3081552-B1 PEST CONTROL AGENT CONTAINING AN AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT MITSUI CHEMICALS AGRO INC (JP) 2021-03-03 EP disclosed
US-10582708-B2 Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative MITSUI CHEMICALS AGRO, INC. (JP) 2020-03-10 US disclosed
EP-2325165-B1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD MITSUI CHEMICALS AGRO INC (JP) 2020-02-19 EP disclosed
US-20170367329-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE MITSUI CHEMICALS CROP & LIFE SOLUTIONS, INC. (JP) 2017-12-28 US disclosed
US-9756856-B2 Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative MITSUI CHEMICALS AGRO, INC. (JP) 2017-09-12 US disclosed
EP-3205642-A2 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE AND PEST CONTROLLING METHOD Mitsui Chemicals Agro, Inc. (JP) 2017-08-16 EP disclosed
EP-2319830-B1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE PEST CONTROL AGENT MITSUI CHEMICALS AGRO INC (JP) 2016-11-02 EP disclosed
EP-3081552-A1 PEST CONTROL AGENT CONTAINING AN AMIDE DERIVATIVE AND USE OF THE PEST CONTROL AGENT Mitsui Chemicals Agro, Inc. (JP) 2016-10-19 EP disclosed
US-9237745-B2 Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative MITSUI CHEMICALS AGRO, INC. (JP) 2016-01-19 US disclosed
US-5476859-A Inhibiting lentivirus by orally administering derivatives of 1,5-dideoxy-1,5-imino-D-glucitol PARTIS RICHARD A (US) 1995-12-19 US disclosed
US-5411970-A Method of inhibiting lentivirus G. D. SEARLE & CO. (US) 1995-05-02 US disclosed
US-5310745-A Acylated derivatives of 1,5-dideoxy-1,5-imino-D-glucitol, AIDS G. D. SEARLE & CO. (US) 1994-05-10 US disclosed
US-5221746-A Inhibitors of visna virus; treatment of AIDS and ARC G. D. SEARLE & CO. (US) 1993-06-22 US disclosed
US-5144037-A Viricides G. D. SEARLE & CO. (US) 1992-09-01 US disclosed
US-4260771-A VASODILATORS, ANTICOAGULANTS, IMMUNOLOGY MERCK & CO., INC. (US) 1981-04-07 US disclosed
US-4225609-A Interphenylene 9-thia-11-oxo-12-aza-prostanoic acids MERCK & CO., INC. (US) 1980-09-30 US disclosed
US-4102888-A VASODILATORS, ANTITHROMBITIC MERCK & CO., INC. (US) 1978-07-25 US disclosed
US-4059587-A 8-AZA-9-OXO-11-THIA-PROSTANOIC ACID DERIVATIVES; VASODILATORS, ANTICLOTTING, REGULATORS OF IMMUNE RESPONSE MERCK & CO., INC. (US) 1977-11-22 US disclosed
US-4022794-A VASODILATION MERCK & CO., INC. (US) 1977-05-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10582708-B2 Amide derivative, pest control agent containing the amide derivative, and use of the amide derivative H1-2, H1-4, H1-0 HIF1A 3771/4885TSHR 1245/4885FAAH 168/4885
US-20170367329-A1 AMIDE DERIVATIVE, PEST CONTROL AGENT CONTAINING THE AMIDE DERIVATIVE, AND USE OF THE AMIDE DERIVATIVE H1-2, H1-4, H1-0 HIF1A 3771/4885TSHR 1245/4885FAAH 168/4885
US-20230234917-A1 ASPARAGINE DERIVATIVES AND METHODS OF USING SAME ASNS, SI, NARS1 HIF1A 3307/4885TSHR 4589/4885FAAH 3546/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.