Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 20/20 | 0.58 |
| ▸ | RARG | P13631 | 19/20 | 0.58 |
| ▸ | RARA | P10276 | 18/20 | 0.58 |
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7807980 | 0.91 | RARB (0.54) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL7807984 | 0.89 | RARA (0.76) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL7807976 | 0.89 | RARA (0.76) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8981781 | 0.88 | RARA (0.77) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8771650 | 0.84 | RARB (0.77) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8661314 | 0.83 | RARB (0.47) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL6238148 | 0.82 | RARB (0.77) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL8043795 | 0.82 | RARB (0.58) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL7807096 | 0.81 | RARB (0.45) | RARBRARGRARARXRANR2E1 | |
| SCHEMBL7807099 | 0.79 | RARB (0.60) | RARBRARGRARARXRANR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5849923-A | Heterocyclic-substituted naphthalenyl retinobenzoic acid derivatives | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-12-15 | — | — | US | disclosed |
| EP-0736530-A2 | Retinoid-like heterocycles | Bristol-Myers Squibb Company (US) | 1996-10-09 | — | — | EP | disclosed |
| US-5559248-A | FOR PREVENTION AND TREATMENT OF SKIN DISORDERS | BRISTOL-MYERS SQUIBB CO. (US) | 1996-09-24 | — | — | US | disclosed |