Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12270047 | 0.80 | RAB9A (0.68) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL12270059 | 0.80 | RAB9A (0.68) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL12787400 | 0.80 | RAB9A (0.68) | RAB9AHTTTSHRALDH1A1GAA | |
| SCHEMBL28383221 | 0.78 | SMN1; SMN2 (0.43) | RAB9APOLBTSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL7803688 | 0.77 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL7803687 | 0.77 | TSHR (0.52) | TSHRALDH1A1 | |
| SCHEMBL794087 | 0.76 | RAB9A (0.50) | RAB9AALDH1A1GAAHSD11B1MEN1 | |
| SCHEMBL24179626 | 0.73 | HTR2C (0.53) | RAB9ASMN1; SMN2 | |
| SCHEMBL3240363 | 0.73 | HTR2C (0.53) | RAB9ASMN1; SMN2 | |
| SCHEMBL29936064 | 0.73 | HTR2C (0.53) | RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5756508-A | Muscarine antagonists | MERCK & CO., INC. (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997016192-A1 | MUSCARINE ANTAGONISTS | MERCK & CO., INC. (US) | 1997-05-09 | — | — | WO | disclosed |