Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140558 | 0.94 | KDM4E (0.42) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL6140783 | 0.93 | KDM4E (0.43) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL3190513 | 0.88 | PTPN1 (0.49) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL6140904 | 0.87 | POLB (0.47) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL6140696 | 0.87 | POLB (0.47) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL6140516 | 0.86 | RAPGEF3 (0.39) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL6139983 | 0.84 | SMN1; SMN2 (0.44) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL6140488 | 0.84 | PSEN1 (0.41) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL6140091 | 0.83 | PTPN1 (0.44) | PTPN1POLBPSEN1PSEN2APH1B | |
| SCHEMBL6140690 | 0.83 | PTPN1 (0.44) | PTPN1POLBPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5847218-A | Sulfonium salts and chemically amplified positive resist compositions | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1998-12-08 | — | — | US | disclosed |