Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 4/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 4/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11281608 | 0.98 | LMNA (0.53) | LMNATP53CYP3A4ALDH1A1SLC1A3 | |
| SCHEMBL14422655 | 0.98 | LMNA (0.53) | LMNATP53CYP3A4ALDH1A1SLC1A3 | |
| SCHEMBL312981 | 0.93 | LMNA (0.53) | LMNATP53CYP3A4ALDH1A1SLC1A3 | |
| SCHEMBL11828571 | 0.91 | LMNA (0.39) | LMNATP53CYP3A4ALDH1A1SLC1A3 | |
| SCHEMBL28376921 | 0.90 | LMNA (0.51) | LMNATP53CYP3A4ALDH1A1SLC1A3 | |
| SCHEMBL15911845 | 0.89 | LMNA (0.48) | LMNATP53CYP3A4ALDH1A1ADRB2 | |
| SCHEMBL26604648 | 0.89 | LMNA (0.46) | LMNATP53CYP3A4ALDH1A1SLC1A3 | |
| SCHEMBL13273682 | 0.89 | LMNA (0.46) | LMNATP53CYP3A4ALDH1A1SLC1A3 | |
| SCHEMBL11282873 | 0.84 | MEN1 (0.38) | LMNATP53CYP3A4ALDH1A1SLC1A3 | |
| SCHEMBL28475888 | 0.84 | LMNA (0.49) | LMNATP53CYP3A4ALDH1A1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1046713-C | Tetrahydroisoquinoline compounds, pharmaceutical compositions containing them, and their preparation and use | KNORR CO LTD (GB) | 1999-11-24 | — | — | CN | disclosed |
| US-5804586-A | ANALGESICS, PSYCHOLOGICAL DISORDERS | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-09-08 | — | — | US | disclosed |
| CN-1128992-A | Therapeutic agents | KNORR CO LTD (DE) | 1996-08-14 | — | — | CN | disclosed |