Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 2/20 | 0.35 |
| ▸ | PYGL | P06737 | 2/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8659761 | 0.93 | MEN1 (0.45) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8660974 | 0.92 | KMT2A (0.47) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8656985 | 0.89 | MEN1 (0.41) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8661107 | 0.89 | MEN1 (0.43) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8658960 | 0.89 | KMT2A (0.49) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8659850 | 0.88 | MEN1 (0.51) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8660963 | 0.88 | PPIA (0.46) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8659795 | 0.87 | KMT2A (0.49) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8657024 | 0.87 | KMT2A (0.45) | MEN1KMT2AMAPTUSP2ALOX15 | |
| SCHEMBL8667813 | 0.86 | MEN1 (0.47) | MEN1KMT2AMAPTUSP2ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| EP-0186297-B1 | PESTICIDAL BIPHENYLYLOXY AND BIPHENYLYLALKOXY ARYL ACYL UREA COMPOUNDS, A PROCESS FOR THEIR PREPARATION, PESTICIDAL COMPOSITIONS AND A METHOD OF CONTROLLING PESTS | RHONE-POULENC NEDERLAND B.V. (NL) | 1989-03-08 | — | — | EP | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| US-4638088-A | INSECTICIDES, MITICIDES | UNION CARBIDE CORPORATION (US) | 1987-01-20 | — | — | US | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0186297-A1 | Pesticidal biphenylyloxy and biphenylylalkoxy aryl acyl urea compounds, a process for their preparation, pesticidal compositions and a method of controlling pests | RHONE-POULENC NEDERLAND B.V. (NL) | 1986-07-02 | — | — | EP | disclosed |