Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25456057 | 0.94 | MAPT (0.66) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL5674267 | 0.89 | HDAC1 (0.75) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL452362 | 0.87 | TDP1 (0.79) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL19561359 | 0.85 | HDAC1 (0.69) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL9404033 | 0.85 | HDAC1 (0.69) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL31596300 | 0.85 | TDP1 (0.76) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL27831457 | 0.85 | HDAC1 (0.69) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL8619264 | 0.84 | CES1 (0.64) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL3286619 | 0.83 | HDAC3 (0.61) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL2342367 | 0.83 | MAPT (0.62) | HDAC1HDAC3HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521262-B | Polydentate beta-diketone ligand, luminescent rare earth complex thereof and application | 复旦大学 | 2021-11-05 | — | — | CN | disclosed |
| CN-112521262-A | Polydentate beta-diketone ligand, luminescent rare earth complex thereof and application | 复旦大学 | 2021-03-19 | — | — | CN | disclosed |
| CN-101423501-A | Heterocycle-containing 5-phenyl-2,4-pentadienyl-1-ones compounds as well as preparation method and application thereof | UNIV CHINA AGRICULTURAL (CN) | 2009-05-06 | — | — | CN | disclosed |
| EP-0686685-B1 | Photochromic dye | RODENSTOCK OPTIK G (DE) | 1998-12-02 | — | — | EP | disclosed |
| EP-0686685-A2 | Photochromic dye | Optische Werke G. Rodenstock (DE) | 1995-12-13 | — | — | EP | disclosed |