SCHEMBL9387441

SCHEMBL9387441

COC(=O)c1cc(N(O)C(=O)OC)ccc1S(=O)(=O)NC(=O)Nc1nc(OC)cc(OC)n1

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.52
CDK1 P06493 2/20 0.51
CYP1A2 P05177 1/20 0.40
TP53 P04637 1/20 0.38
GLA P06280 1/20 0.38
MAPT P10636 1/20 0.38
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9197645 0.93 CDK1 (0.55) GAACDK1CYP1A2TP53GLA
SCHEMBL27544563 0.86 CDK1 (0.38) GAACDK1TP53KMT2AMEN1
SCHEMBL9202913 0.85 CDK1 (0.55) GAACDK1CYP1A2TP53GLA
SCHEMBL8106622 0.83 GAA (0.58) GAACDK1CYP1A2TP53GLA
SCHEMBL1405765 0.82 GAA (0.59) GAACDK1CYP1A2TP53GLA
SCHEMBL9724731 0.80 GAA (0.55) GAACDK1CYP1A2TP53GLA
SCHEMBL9724767 0.79 GAA (0.54) GAACDK1CYP1A2TP53GLA
SCHEMBL27455262 0.79 CDK1 (0.41) GAACDK1TP53KMT2AMEN1
SCHEMBL9080269 0.79 CDK1 (0.62) GAACDK1CYP1A2TP53GLA
SCHEMBL11100011 0.78 GAA (0.55) GAACDK1CYP1A2TP53GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994006778-A1 HYDROXYL AMINO PHENYL SULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT GROWTH REGULATORS HOECHST SCHERING AGREVO GMBH (DE) 1994-03-31 WO disclosed