SCHEMBL8665073

SCHEMBL8665073

C[Si](C)(C)CC#CCO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methyl Alcohol SCHEMBL28712278 0.71
SCHEMBL4173037 0.71
SCHEMBL4577135 0.71
SCHEMBL148914 0.71
SCHEMBL12610779 0.69
SCHEMBL11319167 0.68 ALDH1A1 (0.33)
SCHEMBL12154107 0.68
SCHEMBL787773 0.67
SCHEMBL29131062 0.67
SCHEMBL29165409 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0874866-A1 FREE RADICAL POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1998-11-04 EP disclosed
WO-1997026283-A1 FREE RADICAL POLYMERIZATION THE DOW CHEMICAL COMPANY (US) 1997-07-24 WO disclosed
US-5618900-A Free radical polymerization THE DOW CHEMICAL COMPANY (US) 1997-04-08 US disclosed
US-5536732-A REDUCING INFECTIOUSNESS OF HIV MERRELL PHARMACEUTICALS INC. (US) 1996-07-16 US disclosed
EP-0454580-B1 Novel nojirimycin derivatives MERRELL DOW PHARMA (US) 1995-12-27 EP disclosed
US-5252587-A Viricides, aids therapy, antidiabetic agent MERRELL DOW PHARMACEUTICALS, INC. (US) 1993-10-12 US disclosed
EP-0454580-A2 Novel nojirimycin derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1991-10-30 EP disclosed
EP-0453692-A1 Novel nojirimycin derivatives MERRELL DOW PHARMACEUTICALS INC. (US) 1991-10-30 EP disclosed